Toxicology Books

Drug Information Handbook

Charles F. Lacy

List Price: $49.95 By: Lexi-Comp, Inc. Amazon Marketplace: 20 new & used starting at $0.75

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Customer Reviews:
Total reviews: 29 Average rating: 5.0 of 5

wait, there's more 5 out of 5 stars.
1 of 1 people found this review helpful.

Lexi-Comp's Drug Information Handbook is the bomb. No nagging adds like the PDR; just the facts, ma'am. More eye friendly than previous editions, and still packed with about a gillion tables in the appendix. Drug names are now in red. This is the cat's meow; I probably use it once a day in patient care. Shipping and price are much better through Amazon than through the publisher.

drg information handbook 5 out of 5 stars.
0 of 0 people found this review helpful.

A great quick guide on drug information, perhaps, the best one. Full monographs of almost all of the drugs, including interactions. Much necessary to the pharmacists and other health professionals.

good pharmacy reference 4 out of 5 stars.
0 of 0 people found this review helpful.

just that, a good pharmacy reference. It's a good addition to my other resources and is easy to use.

Editorial Review:

Nevada College of Pharmacy, Las Vegas. Annual quick reference is organized alphabetically by both brand and generic drug names in dictionary format. Includes more than 4,900 US and Canadian medications, more than 1,300 monographs with 34 key fields of information per monograph, and more than 275 pages of appendix information including drug interaction tables.

Basic And Clinical Pharmacology (LANGE Basic Science)

Bertram Katzung

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Customer Reviews:
Total reviews: 34 Average rating: 4.0 of 5

Editorial Review:

The current science of pharmacology-and its clinical applications-at your fingertips

. .

Now in its 25th year of publication, Basic and Clinical Pharmacology is the most up-to-date and complete pharmacology textbook available. Through nine previous editions it has set the standard for concise and easy-to-read, yet comprehensive coverage of pharmacology. The text's integration of basic with clinical science makes it well suited for an integrated organ-system-based curricula as well as the more traditional curricula.

. .

Features

. .

In-depth coverage of key pharmacology topics, from basic principles to pharmacologic considerations for autonomic, cardiovascular-renal, smooth muscle, CNS, endocrine, antimicrobial, and chemotherapeutic and immunotherapeutic drugs . .

Updated with dozens of new, recently approved drugs, including monoclonal antibodies. .

Detailed review of the mechanism of action and toxicities of traditional and newer drugs . .

Critical discussions of treatment strategies and recommended drugs for all major diseases . .

Valuable section on toxicology that provides an introduction to occupational and environmental toxicology; heavy metal intoxication and chelators; and management of the poisoned patient . .

Ready-to-use, study-enhancing features, including special interest boxes, lists of common preparations, and dosage information . .

Unique evidence-based chapters on abused drugs; special aspects of perinatal, pediatric, and geriatric pharmacology; and over-the-counter drugs, herbal medications, and nutritional supplements . .

More than 500 concept-clarifying illustrations and tables throughout . . . . (20070223)

Excitotoxins: The Taste That Kills

Russell L. Blaylock

Amazon Price: $12.21 List Price: $17.95 Usually ships in 24 hours By: Health Press (NM) Amazon Marketplace: 51 new & used starting at $9.50

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Customer Reviews:
Total reviews: 56 Average rating: 4.5 of 5

One for your library 5 out of 5 stars.
5 of 5 people found this review helpful.

This was a great book, a bit hard for a non scientific person, but still great. It is well written by a very knowledgeable person that seems to care. It should be Oprah's book of the month. It you eat, have kids or are concerned about health, then this is the book for you. I do have to warn you, some parts are pretty scary. It was amazing to find out all of the things the government doesn't tell us about our food supply. I can speak to this because I was diagnosed with MS in March of 07' and now I'm aspartame and MS free. I gave up that poison a few months ago and my MS went away within 2 weeks!!!

Real-life experience backs this up 5 out of 5 stars.
3 of 3 people found this review helpful.

I have had this book for many years and recently skimmed it again. I bought it during the years when my husband was having bizarre symptoms after eating almost any kind of food. He visited many doctors and specialists, and an allergist finally suggested that it might be MSG and referred him to a dietician (who was useless). Since then, we've been on our own fighting this, and this book lifted the fog of ignorance!

I'm an engineer, a conservative and a skeptic. I was not ready to believe that there is "bad stuff" in our everyday food. But based on my husband's experiences, the empirical evidence to the contrary is overwhelming. His symptoms initially only occurred after lunch but not after dinner, even if he ate the same thing. How does this make sense? Dr. Blaylock explains the mystery by pointing out how hypoglycemia exacerbates the effects of glutamate. I was ecstatic when I understood the phenomenon. My husband has a tendency, common in his family, toward hypoglycemia. With lunch being his first meal of the day, he was already in a hypoglycemic state and highly susceptible to the effects of MSG. By dinnertime, his brain had more glucose and was better able to clear the glutamate. Based on this theory, when he accidentally eats MSG and starts to experience the effects, he consumes a candy bar or sugared soda and it lessens the symptoms. (Dessert can be good for you!)

The explanations in this book are the only ones that satisfactorily explain what I see my husband go through every day. He has an immediate and recognizable response to glutamate, which makes confirmation of those theories simple, if not painless.

There is one hypothesis in the book that is contradicted by my husband's experience. He can consume aspartame (diet soda) with none of the effects that he experiences from glutamate.

I wonder how many people are capable of making the lifestyle changes required to avoid glutamate? If you don't have a detector (like my poor husband) to tell you what food does and does not have glutamate in it, you must avoid all prepared food that doesn't have an ingredient list. Yes, sadly, glutamate is that prevalent in our food.

The Only Ekg Book You'll Ever Need (4th Edition)

Malcolm S Thaler

List Price: $49.95 By: Lippincott Williams & Wilkins Amazon Marketplace: 16 new & used starting at $33.00

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Customer Reviews:
Total reviews: 25 Average rating: 4.5 of 5

Terrific 5 out of 5 stars.
4 of 4 people found this review helpful.

I've tried Dale Dubin on three different occasions and always gave up midway. This book is easy to read, keeps up your interest, doesn't clog you with unnecessary information, has a good summary at the end of every chapter, good clinical examples are provided and the best part is that it is quite funny. I actually laughed out aloud where he says wolff-parkinson-white and lown-ganong-levine aren't the names of lawfirms!
I managed to finish it in two weeks and it is refreshing to come across an ekg book that doesn't make you want to take extended break times!
Only thing is I wish the author had used more arrows to point out the specific abnormalities and that the last section of practice EKGS was a little more comprehensive.
But I think it is a good resource for residents and students. And I would pick it over Dale Dubin anyday.

Editorial Review:

Now in its updated Fourth Edition, this popular and practical text presents all the information the clinician needs to read EKGs efficiently and accurately. It is an ideal reference for medical students in ICM courses, house officers, or anyone directly involved in patient care, whether student, teacher, or practitioner. This edition includes new information on pacemakers, ischemic heart disease, and myocardial infarction treatment. The book features more than 200 facsimiles of EKG strips and numerous case studies and clinical examples. Also included is a pocket-sized review section that can be removed from the book and added to a pocket notebook.

The Hundred-Year Lie: How to Protect Yourself from the Chemicals That Are Destroying Your Health

Randall Fitzgerald

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Customer Reviews:
Total reviews: 49 Average rating: 4.5 of 5

Editorial Review:

In a devastating exposé in the tradition of Silent Spring and Fast Food Nation, investigative journalist Randall Fitzgerald warns how thousands of man-made chemicals in our food, water, medicine, and environment are making humans the most polluted species on the planet. A century ago in 1906, when Congress enacted the Pure Food and Drug Act, Americans were promised “better living through chemistry.” Fitzgerald provides overwhelming evidence to shatter this myth, and many others perpetrated by the chemical, pharmaceutical, and processed foods industries. In the face of this national health crisis, Fitzgerald also presents informed and practical suggestions for what we can do to turn the tide and live healthier lives.

Consider this:
• The average American carries a “body burden” of 700 synthetic chemicals
• Chemicals in tap water can cause reproductive abnormalities and hermaphroditic birth
• A 2005 study of lactating women in eighteen U.S. states found perchlorate (a toxic component of rocket fuel) in practically every mother’s breast milk

Goodman And Gilman's The Pharmacological Basis of Therapeutics (Goodman and Gilman's the Pharmacological Basis of Therapeutics)

Laurence Brunton, John Lazo, Keith Parker

Amazon Price: $109.17 List Price: $155.00 Usually ships in 24 hours By: McGraw-Hill Professional Amazon Marketplace: 64 new & used starting at $36.97

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Customer Reviews:
Total reviews: 8 Average rating: 4.0 of 5

Get the 10th edition. 2 out of 5 stars.
21 of 25 people found this review helpful.

I can't say that I'm pleased with the new edition. The information is grossly disorganized, there are no introductory chapters, and important information has been omitted or dumbed down, e.g. the section on fat-soluble vitamins, specifically vitamin A.
If you're buying, get the 10th ed. The new edition is definitely a step down for Goodman & Gilman.

A complete Pharmacological Encyclopedia 5 out of 5 stars.
4 of 11 people found this review helpful.

This book is a complete pharmacological encyclopedia from its days of inception.It is useful to any physician as a desk reference.
Professor K.Neelakantan Viswanathan, AVMC, Pondicherry, India

Didn't meet the expectation 3 out of 5 stars.
3 of 5 people found this review helpful.

I have bougth an earlier edition and had great expectation for an update. In my field of interest, psychiatry, it was a disappointment. Could be a good book for students.

Editorial Review:

The undisputed leader in medical pharmacology, without equal. Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the �desert island� book of all medical pharmacology�if you can own just one pharmacology book, this is it. (20060801)

The Detox Book: How to Detoxify Your Body to Improve Your Health, Stop Disease, and Reverse Aging, 2nd Edition

Bruce Fife

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Customer Reviews:
Total reviews: 21 Average rating: 5.0 of 5

Editorial Review:

We live in a toxic world. Environmental pollution and disease-causing germs assault us continually day after day. Our food is nutrient deficient and our water supply dangerously contaminated. People today are exposed to chemicals in far greater concentrations than were previous generations. Diseases that were rare or unheard of a century ago are now raging upon us like a plague. Millions are dying from diseases that were virtually unknown in the past. Experts tell us that by the time we reach middle age, each one of us will have already been affected by either cancer, cardiovascular disease, or some other serious degenerative condition. Conventional medicine has no sure cure. Drugs, surgery, and radiation treatments can be as dangerous and debilitating as the diseases they attempt to cure. This book outlines the steps you need to take to thoroughly detoxify and cleanse your body from these disease-causing agents. You will also learn how to reduce your toxic exposure and how to strengthen your immune system.

Poisoned Profits: The Toxic Assault on Our Children

Philip Shabecoff, Alice Shabecoff

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Total reviews: 6 Average rating: 4.5 of 5

Editorial Review:

In this shocking and sobering book, two fearless journalists directly and definitively link industrial toxins to the current rise in childhood disease and death. In the tradition of Silent Spring, Poisoned Profits is a landmark investigation, an eye-opening account of a country that prizes money over children’s health.

With indisputable data, Philip Shabecoff and Alice Shabecoff reveal that the children of baby boomers–the first to be raised in a truly “toxified” world–have higher rates of birth defects, asthma, cancer, autism, and other serious illnesses than previous generations. In piercing case histories, the authors identify the culprit as corporate pollution. Here are the stories of such places as Dickson, Tennessee, where babies were born with cleft lips and palates after landfill chemicals seeped into the water, and Port Neches, Texas, where so many graduates of a high school near synthetic rubber and chemical plants contracted cancer that the school was nicknamed “Leukemia High.”

The danger to our children isn’t just in the outside world, though. The Shabecoffs provide evidence that our homes are now infested with everything from dangerous flame retardants in crib mattresses to harmful plastic softeners in teething rings to antibiotics and arsenic in chicken–additives that are absorbed by growing and physically vulnerable kids as well as by pregnant women. Compounding the problem are chemical corporations that sabotage investigations and regulations, a government that refuses to police these companies, and corporate-hired scientists who keep pertinent secrets massaged with skewed data of their own.

Poisoned Profits also demonstrates how people are fighting back, whether through grassroots parents’ groups putting pressure on politicians, the rise of “ecotheology” in the pulpits of formerly indifferent churches, or the new “green chemistry” being practiced in labs to replace bad elements with good. The Shabecoffs also include helpful tips on reducing risks to children in how they eat and play, and in how parents clean and maintain their homes.

Powerful, unflinching, and eminently readable, Poisoned Profits is a wake-up call that is bound to inspire talk and force change.

The Crazy Makers: How the Food Industry Is Destroying Our Brains and Harming Our Children

Carol Simontacchi

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Total reviews: 33 Average rating: 4.0 of 5

Enough to Drive Anyone Crazy 1 out of 5 stars.
25 of 30 people found this review helpful.

A review of The Crazy Makers, How the Food Industry is Destroying Our Brains and Harming Our Children, by Carol Simontacchi

By Gregory Ziegler
Professor of Food Science
Penn State University

Rational thought is not what you will find in The Crazy Makers, How the Food Industry is Destroying Our Brains and Harming Our Children, by Carol Simontacchi. Instead, what you will read is a quasi-scientific, religious polemic against "food manufacturing." The book's thesis statement is that "diet is the one major change in our culture over the past century that has altered the physical state of our brains and, therefore, altered the state of our minds."

The religious nature of the book is evident from the very beginning, where in the Acknowledgements Ms. Simontacchi thanks most of all her "Heavenly Father, who designed the most wonderful food, perfectly suited to nourishing our brains and our spirits. We have turned aside from Your providence and tried to manufacture our own. How foolish of us."

I must come clean. I am the Director of Penn State's Center for Food Manufacturing, and some would consider me a shill for the "food industry." However, my critique of this book should not be construed as a defense of food manufacturers, but as a guide to those who would like to separate rational thought from opinion.

Though a "board-certified clinical nutritionist," Simontacchi apparently does not know that neither cholesterol nor phosphatidylserine are fatty acids, that glutathione is not an amino acid, or that phytic acid is not a protein. Glutamic acid is a non-essential amino acid building block of proteins. Non-essential means that while we need glutamic acid to build proteins, our body can make its own and, therefore, it is not required in the diet. Mono sodium glutamate is the sodium salt of this amino acid. Simontacchi refers to MSG as an excitotoxin, and writes that "glutamate, is embedded in other ingredients commonly added to baby food," but fails to inform the reader that these other ingredients are proteins or that glutamic acid is by far the most common amino acid in human milk casein.

Is glutamate natural asks Simontacchi. As natural as mother's milk. Might it be harmful in excess? Yes it might. But the idea that something natural may also be toxic goes against Simontacchi's basic assumption of "natural goodness." In the lead-in to chapter 6 Simontacchi quotes Isaiah 55:2, "Why do you spend money for what is not bread." Yet the gluten proteins of bread are about 35% glutamic acid (in the form of glutamine), and says Simontacchi, "[G]rain allergies are one of the most common sources of depression." (More on bread later.)

Glutamic acid is heralded as "brain food" in the chapter "Feeding the Autistic Brain."

While appearing scientific in approach, Simontacchi shows obvious distain for proper scientific methods. She states emphatically that the "influence of a high-sugar diet on brain chemistry is enormous," despite the fact that contradictory "meta-analyses" of the research on the issue were published in both the American Journal of Clinical Nutrition and the Journal of the American Medical Association. She refers to these meta-analyses simply as "a review article," and then presumes to "balance" the argument by quoting an article from the South African Medical Journal. The title of the article she uses to assert the effect of sugar on behavior - "Is butter bad for you?" But then she has already warned us not to believe the experts, and "that virtually everything written about nutrition in the mainstream press is wrong." Does sugar affect the brain? Forget science, "just ask Miss Redman or any schoolteacher. Ask mom."

The section "The Current State of Our Minds" appears to be a litany of Ms. Simontacchi's greatest fears and anxieties. Much of what is written is unsupported by data. She quotes Harvard Medical School professor Ronald Kessler as saying, "The trends are sufficiently impressive to fuel speculation that upward trends in mental illness might exist," [emphases mine] and then follows that with the statement "[W]ithin our current mental health epidemic." How did a speculation of what might be end up an epidemic?

Even when the data contradict her assertions - "[R]ates of violence seem to be easing off" - Simontacchi persists in spinning it to meet her expectations - "But the U.S. surgeon general is not letting his guard down." "Even more bleakly," violent tendencies have not lessened over the past fifteen years (nor have they apparently increased), and arrests for aggravated assault "declined only slightly." Definitely a glass-is-half-empty perspective. "Skyrocketing," "growing trend," "taking on major proportions" and "growing numbers" are all phrases used to hype the problems without substantiating data. Simontacchi cites little primary scientific literature, relying instead on secondary references, many of which are not credible.

Simontacchi's lack of scientific integrity is demonstrated when she cites the "Pottenger" study as evidence of the harmful effects of milk pasteurization. Dr. Pottenger's cats became ill due to a lack of the amino acid taurine, which resulted from too little meat in their diets. Simontacchi fails to tell the reader that cats fed on raw milk only fared worse than those on a combination of meat and pasteurized milk. Pasteurization is a mild heat treatment intended to destroy the living cells of potential human pathogens. Along with improvements in hygiene, milk pasteurization probably did as much as anything to improve human health in the 20th Century.

While condemning pasteurized milk as a "highly processed dairy food," Simontacchi seems to encourage the consumption of tofu, despite the fact that many more steps are required to manufacture tofu from soybeans. These steps include heating to temperatures well in excess of those required for milk pasteurization. Furthermore, tofu contains the same phytoestrogens that Simontacchi says make soy-based infant formula even worse than milk-based products. And the magnesium in tofu? Magnesium chloride, technically a food additive.

This begs the questions, what is "processed" food, and why are "manufactured" foods "chilling." Does cooking a meal at home in a manner similar to pasteurization result in a "highly processed" food? Manufacturing simply means to be made from raw materials by hand or by machine, so a home baker is by definition a manufacturer. The Eucharist is a manufactured food, bread does not exist in Nature, and so is the "protein breakfast drink" (likely loaded with glutamic acid) that Simontacchi suggests for the adolescent breakfast.

Like similar polemics on the topic, the book is replete with nostalgia for a bygone era when we all just picked food fresh from our backyard Eden and is heavily laden with inflammatory language, but adds an evangelistic tone. "The epidemic of autism is just one facet of a nation that has lost its moral way." Simontacchi dismisses reports by the Centers for Disease Control and the Institutes of Medicine finding no link between mercury in vaccines and autism*, insisting that it's a matter of "common sense."

So what's the harm in Ms. Simontacchi dismissing the best science and expressing her opinion? It diverts our attention from investigating other more likely causes of our problems. For example, while Simontacchi does mention in passing that physicians often recommend a strict gluten-free and casein-free diet for autistic children, she never discusses the potential relationship between autism and Celiac's disease. Could it be that she can't imagine such a thing could be caused by whole grains, one of God's most wonderful foods?

Nutritionists like Simontacchi once told us to substitute margarine for Mother Nature's butter, a recommendation we have now come to regret. Now they are telling us to eat lots of whole grain. "Whom are we to believe?"


* Since 2001, with the exception of some influenza (flu) vaccines, mercury-containing thimerosal is not used as a preservative in routinely recommended childhood vaccines.

Editorial Review:

An unprecedented and impeccably reported look at how American food manufacturers and their "products" may be endangering our minds.

With obesity becoming one of the fastest-growing worldwide epidemics, and manufactured food fueling that trend, The Crazy Makers is timelier than ever. This updated edition includes a new chapter on autism, as well as revised material that illustrates just how much the industry has changed in a few short years.

Based on extensive research, epidemiological evidence, and a formal study of schoolchildren's eating habits, The Crazy Makers identifies how the latest food products may be literally driving us crazy. Carol Simontacchi offers the reader nutritional primers and recipes to help counteract the problems facing us and our children every time we sit down to eat.

The Body Toxic: How the Hazardous Chemistry of Everyday Things Threatens Our Health and Well-being

Nena Baker

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Total reviews: 10 Average rating: 4.5 of 5

Editorial Review:

We are running a collective chemical fever that we cannot break. Everyone everywhere now carries a dizzying array of chemical contaminants, the by-products of modern industry and innovation that contribute to a host of developmental deficits and health problems in ways just now being understood. These toxic substances, unknown to our grandparents, accumulate in our fat, bones, blood, and organs as a consequence of womb-to-tomb exposure to industrial substances as common as the products that contain them. Almost everything we encounter—from soap to soup cans and computers to clothing—contributes to a chemical load unique to each of us. Scientists studying the phenomenon refer to it as “chemical body burden,” and in The Body Toxic, the investigative journalist Nena Baker explores the many factors that have given rise to this condition—from manufacturing breakthroughs to policy decisions to political pressure to the demands of popular culture. While chemical advances have helped raise our standard of living, making our lives easier and safer in many ways, there are costs to these conveniences that chemical companies would rather consumers never knew about. Baker draws back the curtain on this untold impact and assesses where we go from here.